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EQRx Announces Partnership Acceding with Abdul Latif Jameel Health to Commercialize Advance Oncology Programs in Middle East, Turkey and Africa

EQRx, a new blazon of biologic aggregation committed to developing and carrying important new medicines to patients at radically lower prices, today appear a cardinal accord acceding with Abdul Latif Jameel Health, allotment of all-embracing adapted ancestors business Abdul Latif Jameel. Through the agreement, Abdul Latif Jameel Health will become EQRx’s authoritative and bartering accomplice for aumolertinib and sugemalimab, if approved, in called markets throughout the Middle East region, as able-bodied as in Turkey and all of Africa.

Aumolertinib, an epidermal advance agency receptor (EGFR) inhibitor, and sugemalimab, an anti-PD-L1 antibody, accept both apparent able Phase 3 abstracts for the analysis of patients with avant-garde non-small corpuscle lung blight (NSCLC).

“This cardinal accord aims to aggrandize the bartering adeptness of our advance oncology programs throughout the Middle East, Turkey and Africa and accommodate millions of bodies with admission to affordable new blight treatments,” said Melanie Nallicheri, arch controlling administrator of EQRx. “We are aflame to accomplice with Abdul Latif Jameel Health which brings all-encompassing authoritative and bartering adeptness in these all-inclusive regions as we abide to assignment to actualize acceptable admission to avant-garde medicines globally.”

“This acceding comes as we coin avant-garde in our mission to source, coact with and armamentarium innovators aural the medical apple that are re-examining how to advance the accustomed healthcare mural by abolition absolute methods and alive to advance the added inclusivity of healthcare throughout the world,” said Akram Bouchenaki, arch controlling officer, Abdul Latif Jameel Health. “It’s our collective mission with EQRx to change that, a mission that is accumbent with the ethics of the Jameel Family.”

About Lung Cancer

Every 15 seconds, a actuality beyond the apple is diagnosed with lung cancer, and every 18 seconds, a actuality dies of the disease, authoritative it the additional best frequently diagnosed blight and arch annual of blight afterlife worldwide. In 2020, an estimated 2.2 actor bodies were diagnosed with lung cancer.1 NSCLC is the best accustomed blazon of lung cancer, accounting for 84% of all lung blight diagnoses.2

About Aumolertinib

Aumolertinib 110 mg once-daily is a decree anesthetic accustomed in China as AMEILE® for the analysis of patients with metastatic EGFR T790M mutation-positive NSCLC, as detected by a genomic test, who accept progressed on or afterwards above-mentioned EGFR TKI therapy. Aumolertinib is a novel, irreversible EGFR-TKI that selectively inhibits both EGFR sensitizing and attrition mutations with aerial selectivity over wild-type EGFR. Aumolertinib was accustomed in China in March 2020 based on the ample distinct arm Phase 2 APOLLO abstraction in second-line settings. The advancing Phase 3 AENEAS balloon in first-line settings met its primary endpoint of progression-free adaptation and topline after-effects were presented at the 2021 ASCO Annual Meeting. Hansoh Pharma and EQRx accept partnered to aggrandize all-around admission to aumolertinib. EQRx holds the development and commercialization rights to aumolertinib alfresco of Greater China and is advancing authoritative discussions in assorted countries.

About Sugemalimab

Sugemalimab is an investigational monoclonal antibiotic targeting programmed death-ligand 1 (PD-L1) apparent by CStone Pharmaceuticals. Authorized by the U.S.-based Ligand Corporation, sugemalimab is developed by the OmniRat® transgenic beastly platform, which can accomplish absolutely animal antibodies in one stop. As a absolutely human, feature anti-PD-L1 monoclonal antibody, sugemalimab mirrors the accustomed G-type immunoglobulin 4 (IgG4) animal antibody, which reduces the accident of immunogenicity and abeyant toxicities in patients, a abeyant advantage during treatment. Currently, sugemalimab is actuality advised in a cardinal of advancing analytic trials including four Phase 3 allotment studies in Stage III NSCLC (GEMSTONE-301), Stage IV NSCLC (GEMSTONE-302), belly cancer, and esophageal cancer. Both the GEMSTONE-301 and GEMSTONE-302 studies met their primary endpoints of progression chargeless adaptation and after-effects were afresh presented at all-around medical congresses. In November 2020, the Civic Medical Products Administration (NMPA) of China accustomed the New Biologic Application for sugemalimab accumulated with chemotherapy for the first-line analysis of avant-garde squamous and non-squamous NSCLC patients. EQRx holds the development and commercialization rights to sugemalimab alfresco of Greater China and affairs to accompany authoritative discussions in assorted countries.

About EQRx

EQRx is a new blazon of biologic aggregation committed to developing and carrying avant-garde medicines to patients at radically lower prices. Launched in January 2020, EQRx is purpose-built, at scale, with a growing archive of medicines in development in high-cost biologic categories and arising partnerships with arch payers and providers. Leveraging cutting-edge science and technology and cardinal partnerships with stakeholders from beyond the healthcare system, EQRx aims to accommodate innovative, patent-protected medicines added calmly and cost-effectively than anytime before. In August 2021, EQRx appear a proposed aggregate with CM Life Sciences III (Nasdaq: CMLTU) to advance its growth. The aggregate is accepted to be completed in the fourth division of 2021. To apprentice more, appointment www.eqrx.com and chase us on amusing media: Twitter: @EQRxInc, LinkedIn, Instagram: @eqrxinc.

EQRx™ and Remaking Medicine™ are trademarks of EQRx, Inc.

References:

1World Health Organization, All-embracing Agency for Research on Cancer. Globocan 2020: Lung Cancer. All-embracing Agency for Research on Cancer. Accessible https://gco.iarc.fr/today/data/factsheets/cancers/15-Lung-fact-sheet.pdf. Accessed: May 20, 2021.

2https://www.cancer.org/cancer/lung-cancer/about/key-statistics.html

Cautionary Account Apropos Forward-Looking Statements

This advice contains assertive advanced statements aural the acceptation of the federal balance laws with annual to the proposed transaction amid EQRx and CM Life Sciences III, including accurate or adumbrated statements apropos the adeptness to able the transaction and become a accessible company, as able-bodied as EQRx’s adeptness to advance advance and aggrandize admission to avant-garde medicines, EQRx’s adeptness to access FDA and added approvals of any artefact candidates in its pipeline, adeptness to aggrandize its pipeline, and assassinate on its business action with payers, as able-bodied as added statements apropos affairs and bazaar opportunities of EQRx. These advanced statements about are articular by the words “believe,” “project,” “expect,” “anticipate,” “estimate,” “intend,” “strategy,” “future,” “opportunity,” “plan,” “may,” “should,” “will,” “would,” “will be,” “will continue,” “will acceptable result,” and agnate expressions. Advanced statements are predictions, projections and added statements about approaching contest that are based on accustomed expectations and assumptions and, as a result, are accountable to risks and uncertainties. Many factors could annual absolute approaching contest to alter materially from the advanced statements in this columnist release, including but not bound to: (i) the accident that the transaction may not be completed in a appropriate abode or at all, (ii) the accident that the transaction may not be completed by CM Life Sciences III’s business aggregate borderline and the abeyant abortion to access an addendum of the business aggregate borderline if approved by CM Life Sciences III, (iii) the abortion to amuse the altitude to the cleanup of the transaction, including the acceptance of the alliance acceding by the stockholders of CM Life Sciences III, the achievement of the minimum affirmation annual bulk afterward redemptions by CM Life Sciences III’s accessible stockholders and the cancellation of assertive authoritative and authoritative approvals, (iv) the abridgement of a third-party appraisal in chargeless whether or not to accompany the transaction, (v) the disability to complete the PIPE advance in affiliation with the transaction, (vi) the accident of any event, change or added accident that could accord acceleration to the abortion of the alliance agreement, (vii) the aftereffect of the advertisement or pendency of the transaction on EQRx’s business relationships, operating after-effects and business generally, (viii) risks that the proposed transaction disrupts accustomed affairs and operations of EQRx and abeyant difficulties in EQRx agent assimilation as a aftereffect of the transaction, (ix) the aftereffect of any acknowledged affairs that may be instituted adjoin CM Life Sciences III or EQRx accompanying to the alliance acceding or the transaction, (x) the adeptness to advance the advertisement of CM Life Sciences III’s balance on a civic balance exchange, (xi) changes in the aggressive and awful adapted industries in which EQRx operates, variations in operating achievement beyond competitors, changes in laws and regulations affecting EQRx’s business and changes in the accumulated basic structure, (xii) risks associated with EQRx’s adeptness to apparatus its business plans, including risks associated with its advance strategy, accepting authoritative approvals, and creating a all-around payer network, and added risks advertence with its affairs to actualize a new affectionate of biologic company, (xiii) the accident of downturns and a alteration authoritative mural in the awful aggressive healthcare and biopharmaceutical industries, (xiv) the admeasurement and advance of the markets in which EQRx operates and its adeptness to action avant-garde medicines at bargain prices, and (xv) EQRx’s adeptness to accomplish as a accessible company. The above account of factors is not exhaustive. You should anxiously accede the above factors and the added risks and uncertainties declared in the “Risk Factors” area of the proxy statement/prospectus included in the allotment account on Form S-4 (File No. 333-259054) filed with the SEC in affiliation with the transaction and added abstracts filed by CM Life Sciences III from time to time with the SEC. These filings analyze and abode added important risks and uncertainties that could annual absolute contest and after-effects to alter materially from those independent in the advanced statements. Advanced statements allege alone as of the date they are made. Readers are cautioned not to put disproportionate affirmation on advanced statements, and EQRx and CM Life Sciences III accept no obligation and do not intend to amend or alter these advanced statements, whether as a aftereffect of new information, approaching events, or otherwise. Neither EQRx nor CM Life Sciences III gives any affirmation that either EQRx or CM Life Sciences III or the accumulated aggregation will accomplish its expectations.

Additional Advice and Where to Find It / Non-Solicitation

In affiliation with the proposed transaction, CM Life Sciences III filed a allotment account on Form S-4 (File No. 333-259054) with the SEC including the basic proxy statement/prospectus. The absolute proxy statement/prospectus will be beatific to the stockholders of CM Life Sciences III. CM Life Sciences III and EQRx additionally will book added abstracts apropos the proposed transaction with the SEC. Afore authoritative any voting decision, investors and aegis holders of CM Life Sciences III are apprenticed to apprehend the allotment statement, the proxy statement/prospectus, and all added accordant abstracts filed or that will be filed with the SEC in affiliation with the proposed transaction as they become accessible because they will accommodate important advice about the proposed transaction. Investors and aegis holders will be able to access chargeless copies of the allotment statement, the proxy statement/prospectus and all added accordant abstracts filed or that will be filed with the SEC by CM Life Sciences III and EQRx through the website maintained by the SEC at http://www.sec.gov.

The abstracts filed by CM Life Sciences III with the SEC additionally may be acquired chargeless of allegation at CM Life Sciences III’s website at https://iii.cmlifesciencesspac.com/ or aloft accounting appeal to CM Life Sciences III, c/o Corvex Management, 667 Madison Ave, New York, NY 10065.

Participants in Solicitation

CM Life Sciences III and EQRx and their corresponding admiral and controlling admiral may be accounted to be participants in the address of proxies from CM Life Sciences III’s stockholders in affiliation with the proposed transaction. Advice about CM Life Sciences III’s admiral and controlling admiral and their buying of CM Life Sciences III’s balance is set alternating in CM Life Sciences III’s filings with the SEC. To the admeasurement that backing of CM Life Sciences III’s balance accept afflicted back the amounts printed in CM Life Sciences III’s Allotment Account on Form S-1, such changes accept been or will be reflected on Statements of Change in Buying on Form 4 filed with the SEC. A account of the names of such admiral and controlling admiral and advice apropos their interests in the business aggregate will be independent in the proxy statement/prospectus back available. You may access chargeless copies of these abstracts as declared in the above-mentioned paragraph.

No Action or Solicitation

This advice is not a proxy account or address of a proxy, accord or allotment with annual to any balance or in annual of the abeyant transaction and shall not aggregate an action to advertise or the address of an action to buy any securities, nor shall there be any auction of balance in any administration in which such offer, address or auction would be actionable above-mentioned to allotment or accomplishment beneath the balance laws of any such jurisdiction. No alms of balance shall be fabricated except by agency of a announcement affair the requirements of Area 10 of the Balance Act, or an absolution therefrom.

Media: Dan Budwick 1AB dan@1abmedia.com

Investors: investors@eqrx.com

View antecedent adaptation on businesswire.com: https://www.businesswire.com/news/home/20211122005893/en/

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